Hypervitaminosis D

All Th1 inflammatory diseases are characterized by dysregulated Vitamin D metabolism caused by an abnormal immune system response to intracellular bacteria. This results in an elevated level of the active metabolite 1,25-Dihydroxyvitamin-D. This is known as hypervitaminosis-D. Hypervitaminosis-D is characterized by: Fatigue Asthenia (loss of strength and energy) Insomnia (difficulty falling asleep or staying asleep) Somnolence (sleepiness) Paresthesia (numbness, tingling, burning, prickling) Facial palsy (paralysis; usually unilateral) Metallic taste Irritability Mood or mental changes Memory loss Inability to concentrate Dysphonia (difficulty speaking) Dryness of mouth Arthralgia (pain where there should be no pain) Podagra (pain in the great toe) Muscle, bone and joint pain (ankles especially) Muscle cramps Tightening of throat muscles, difficulty swallowing Muscle paralysis Muscle problems leading to difficulty breathing (dyspnea) Stiffness Loss of muscle control Loss of balance Uncoordinated movement Dysphagia (difficulty swallowing) Vertigo (a feeling of spinning) Dizziness, lightheadedness Feeling of intoxication Irregular heartbeat Loss of sex drive Tinnitus (ringing in ears) Hearing loss Nasal/sinus congestion Diarrhea Constipation Cloudy urine Abdominal discomfort Nausea/vomiting Anorexia (loss of appetite) Photosensitivity (intolerance of light) Irritated eyes Redness of eyelid or lining of eyelid Conjunctivitis (redness or discharge of eye) Cloudy-looking eyes Runny nose Frequent, Excruciating Migraines Headaches (continuing) Hyperthermia (feeling too warm) Night sweats Cough Pruritus (itching skin) Hypercalcemia (excessive calcium in blood) causing weight loss and anemia Bone demineralization (osteoporosis) Calcium deposits in soft tissues of lungs, heart, blood vessels, renal tubules Kidney stones Impaired renal function causing: polyuria (excessive urination) nocturia (excessive urination at night) polydipsia (excessive thirst) calciuria (calcium in urine) azotemia (nitrogen in urine) proteinuria (protein in urine) Irreversible renal insufficiency Late symptoms of severe overdose: high blood pressure, high fever, severe stomach pain The effects of administered Vitamin D can persist for two or more months after cessation of treatment.